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cihr_grants: 170403

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external_id title project_lead_name co_researchers institution province country competition_year award_amount program program_type theme research_subject keywords abstract duration source_url
170403 Regulation of the gene transfer agent (GTA) of Rhodobacter capsulatus Beatty John Thomas Beatty, John Thomas University of British Columbia British Columbia Canada 200809 512507.0 Operating Grant Operating Grants Biomedical Genetics Bacteria; Dna Virus; Gene Transfer Agent; Genetic Exchange; Molecular Biology This work is to study how a bacterial cell controls the production of a virus-like particle (the gene transfer agent, or GTA) that has the sole function of transfering genes from a donor to a recipient cell. Our preliminary work indicates aspects of several changes in environmental conditions, such as the presence or absence of specific chemicals, that affect gene transfer. We wish to determine exactly how such chemicals, or 'signals', are sensed by cells and the biochemical pathways leading from signal sensation to the turn on/off of GTA genes. 5 yrs 0 mth https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=170403&lang=en
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